Meningitis occurs when the lining of the brain and spinal cord (meninges) becomes inflamed. Cerebrospinal fluid (CSF), a clear fluid that surrounds and protects the brain and spinal cord, has an increased number of white blood cells. Aseptic meningitis occurs when there are signs of meningitis without an identifiable disease-causing agent.
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The most common causes of aseptic meningitis are:
- Viral infections:
- Bacterial infections, such as tuberculosis
- Parasitic infections, such as Lyme disease
- Mycoplasma, an usual bacteria that can cause pneumonia
- Partially treated bacterial meningitis
- Autoimmune disorders, such as systemic lupus erythematosus or sarcoidosis
- Cancer that has spread to the meninges
- Certain medications
Aseptic meningitis affects children and teens more than adults. Other factors that may increase your chance of developing aseptic meningitis include:
- Being exposed to someone with a viral illness
- The season—mostly occurs in late spring and summer
- Working in a daycare or healthcare setting
- Having a compromised immune system
- Taking certain medications, such as non-steroidal anti-inflammatory drugs (NSAIDs) or medications injected directly into the CSF
Aseptic meningitis may cause:
- Fever and chills
- Stiff neck
- General feeling of illness
- Sore throat
- Muscle or abdominal pain
- Mental confusion
- Sensitivity to light
- Nausea or vomiting
Your doctor will ask about your symptoms and medical history. A physical exam will be done.
You may need to have samples taken of your bodily fluids. This can be done with:
- Blood tests
- Lumbar puncture —to evaluate CSF
Imaging tests can evaluate the brain and surrounding structures. This can be done with:
Talk with your doctor about the best treatment plan for you. Most cases of aseptic meningitis improve with time. Treatment options include:
- Supportive care—Your doctor may recommend that you rest and drink plenty of fluids. You may need to be hospitalized to be monitored and to stay hydrated.
Medications—If specific causes of meningitis are suspected, your doctor may advise that you take:
- Antivirals—for viral infection
- Antibiotics—for bacterial infection
- Antifungals—for fungal infection
- Pain relievers—to relieve symptoms
- Steroids—to reduce inflammation
- In certain cases, your doctor may advise that you stop some medications.
Note: Aspirin is not recommended for children with a current or recent viral infection. Check with your doctor before giving your child aspirin.
To help reduce your chance of aseptic meningitis:
- Wash your hands
often, especially if you:
- Are in close contact with a person who has an infection
- Changed the diaper of an infant with an infection
- If you work in a childcare or healthcare setting, clean objects and surfaces
- Be sure all of your vaccinations are up-to-date
National Meningitis Association http://www.nmaus.org
Meningitis Research Foundation of Canada http://www.meningitis.ca
Updated July 8, 2010. Accessed May 29, 2014.
Ginsberg L, Kidd D. Chronic and recurrent meningitis. Pract Neurol. 2008;8(6):348-361.
Jolles S, Sewell WA, Leighton C. Drug-induced aseptic meningitis: diagnosis and management. Drug Saf. 2000;22(3):215-226.
Meningococcal disease. Centers for Disease Control and Prevention website. Available at:
Updated April 1, 2014. Accessed May 29, 2014.
Norris C, Danis P, Gardner T. Aseptic meningitis in the newborn and young infant. Am Fam Physician. 1999;59(10):2761-2770.
Last Updated: 5/29/2014